In 2010, a clinical study has demonstrated that the use of Saffron improves the sensitivity of the retina in the initial stages of macular degeneration (AMD). The purpose of the subsequent studies was to assess whether the functional benefits observed, could extend for a longer duration, even at later stages of the disease. In 2012, a new, dedicated research involved twenty-nine patients in the age group between 55 and 85 years with visual acuity> 0.3 and subjected them to the administration of 20mg of saffron a day, for a total period of 14 months. After the first three months of treatment, were recorded major improvements in the sensitivity of the retina and visual acuity. The changes remained stable during the subsequent period of follow-up, confirming the effectiveness of Saffron for those suffering from macular degeneration (AMD) in the long term. For more details on the research, the paper is available at the link