It has been recently published on “OK Salute e Benessere” an interview with Prof Bisti who reported interesting results obtained both in preclinical as well as in clinical studies where saffron treatment was used to cope with neurodegenerative processes of neuro-retina. Clinical trials performed by the team of Prof. Falsini at Policlinico Gemelli provide convincing evidence of maintenance of visual functions in patients with age related macular degeneration (AMD). In addition the chemical composition of active brands of saffron have been clarified and patented and neuroprotective saffron was named “repron”. Repron® was used in both preclinical and clinical studies. Results have been published in international peer reviewed papers.